The Protective Effect of Melittin on Renal Fibrosis in an Animal Model of Unilateral Ureteral Obstruction.

@article{An2016ThePE,
  title={The Protective Effect of Melittin on Renal Fibrosis in an Animal Model of Unilateral Ureteral Obstruction.},
  author={Hyun Jin An and Jung-Yeon Kim and Woon-Hae Kim and Sang Mi Han and Kwan-Kyu Park},
  journal={Molecules},
  year={2016},
  volume={21 9}
}
Renal fibrosis is the principal pathological process underlying the progression of chronic kidney disease that leads to end-stage renal disease. Melittin is a major component of bee venom, and it has anti-bacterial, anti-viral, and anti-inflammatory properties in various cell types. Thus, this study examined the therapeutic effects of melittin on the progression of renal fibrosis using the unilateral ureteral obstruction (UUO) model. In addition, the effects of melittin on inflammation and… CONTINUE READING