The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation.

@article{Ramon2016ThePP,
  title={The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation.},
  author={Sesquile Ramon and Jesmond Dalli and Julia M. Sanger and Jeremy W. Winkler and Marius Aursnes and J\orn Eivind Tungen and Trond V Hansen and Charles N Serhan},
  journal={The American journal of pathology},
  year={2016},
  volume={186 4},
  pages={962-73}
}
Inflammation and its natural resolution are host-protective responses triggered by infection or injury. The resolution phase of inflammation is regulated by enzymatically produced specialized pro-resolving mediators. We recently identified a new class of peptide-conjugated specialized pro-resolving mediators that carry potent tissue regenerative actions that belong to the protectin family and are coined protectin conjugates in tissue regeneration (PCTR). Herein, with the use of microbial… CONTINUE READING
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