The Propionic Acids: A Personal Perspective

@article{Adams1992ThePA,
  title={The Propionic Acids: A Personal Perspective},
  author={S. S. Adams},
  journal={The Journal of Clinical Pharmacology},
  year={1992},
  volume={32}
}
  • S. S. Adams
  • Published 1992
  • Medicine
  • The Journal of Clinical Pharmacology
  • In searching during the early 1950s for new drugs for the treatment of rheumatoid arthritis, little information was available to allow a rational approach. The mode of action of the few drugs available was unknown and even the analgesic action of aspirin could not be demonstrated in animals. A speculative concept was developed that aspirin possessed a specific unidentified action in rheumatoid arthritis and that this and its analgesic properties were related to its ability to delay the… CONTINUE READING
    60 Citations
    50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams
    • 15
    • Highly Influenced
    Over-the-counter analgesics and antipyretics: a critical assessment.
    • 165
    The discovery and development of antiinflammatory drugs.
    • 69
    [A short history of anti-rheumatic therapy. III. Non steroidal anti-inflammatory drugs].
    • 2
    • PDF
    Choosing the Right Nonsteroidal Anti-Inflammatory Drug for the Right Patient
    • 66
    Acyl glucuronides: the good, the bad and the ugly.
    • 118
    Influence of piperine on ibuprofen induced antinociception and its pharmacokinetics.
    • 17

    References

    SHOWING 1-10 OF 43 REFERENCES
    Perspectives in nonsteroidal anti-inflammatory agents.
    • T. Y. Shen
    • Chemistry, Medicine
    • Angewandte Chemie
    • 1972
    • 155
    Clinical Safety of Flurbiprofen
    • 16
    The metabolism of ibuprofen.
    • 203
    Stereoselective disposition of ibuprofen enantiomers in man.
    • 91