The Propionic Acids: A Personal Perspective

  title={The Propionic Acids: A Personal Perspective},
  author={S. S. Adams},
  journal={The Journal of Clinical Pharmacology},
  • S. S. Adams
  • Published 1992
  • Medicine
  • The Journal of Clinical Pharmacology
  • In searching during the early 1950s for new drugs for the treatment of rheumatoid arthritis, little information was available to allow a rational approach. The mode of action of the few drugs available was unknown and even the analgesic action of aspirin could not be demonstrated in animals. A speculative concept was developed that aspirin possessed a specific unidentified action in rheumatoid arthritis and that this and its analgesic properties were related to its ability to delay the… CONTINUE READING
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