The Propionic Acids: A Personal Perspective

@article{Adams1992ThePA,
  title={The Propionic Acids: A Personal Perspective},
  author={S. S. Adams},
  journal={The Journal of Clinical Pharmacology},
  year={1992},
  volume={32}
}
  • S. Adams
  • Published 1 April 1992
  • Medicine
  • The Journal of Clinical Pharmacology
In searching during the early 1950s for new drugs for the treatment of rheumatoid arthritis, little information was available to allow a rational approach. The mode of action of the few drugs available was unknown and even the analgesic action of aspirin could not be demonstrated in animals. A speculative concept was developed that aspirin possessed a specific unidentified action in rheumatoid arthritis and that this and its analgesic properties were related to its ability to delay the… 
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The Use of Ibuprofen in the Treatment of Postoperative Pain in Dentistry
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The aim of this article was to present the most important pharmacological and therapeutic characteristics and side effects of ibuprofen used for postoperative pain treatment in dentistry.
Review on analgesic effect of co-administrated ibuprofen and caffeine
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Researchers showed that caffeine can be an effective analgesic adjuvant enhancing antinociceptive effect of ibuprofen in animals and humans and tablets containing well-soluble ib uprofen salt and caffeine could be easily prepared.
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