The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

@inproceedings{Cooper2010ThePM,
  title={The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas},
  author={Lee A. D. Cooper and David A. Gutman and Qi Long and Brent A. Johnson and Sharath R. Cholleti and Tahsin M. Kurç and Joel H. Saltz and Daniel J. Brat and Carlos S. Moreno},
  booktitle={PloS one},
  year={2010}
}
The Cancer Genome Atlas Project (TCGA) has produced an extensive collection of '-omic' data on glioblastoma (GBM), resulting in several key insights on expression signatures. Despite the richness of TCGA GBM data, the absence of lower grade gliomas in this data set prevents analysis genes related to progression and the uncovering of predictive signatures. A complementary dataset exists in the form of the NCI Repository for Molecular Brain Neoplasia Data (Rembrandt), which contains molecular and… CONTINUE READING

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