The Production IL-21 and VEGF in UVB-irradiated Human Keratinocyte Cell Line, HaCaT

@inproceedings{Kim2010ThePI,
  title={The Production IL-21 and VEGF in UVB-irradiated Human Keratinocyte Cell Line, HaCaT},
  author={Hyemin Kim and Jae Seung Kang and Wang Lee},
  booktitle={Immune network},
  year={2010}
}
BACKGROUND Ultraviolet B (UVB) induces multiple inflammatory and carcinogenic reactions. In skin, UVB induces to secrete several kinds of inflammatory cytokines from keratinocytes and also increases angiogenic process via the modulation of vascular endothelial growth factor (VEGF) production. Interleukin-21 (IL-21) is an inflammatory cytokine and produced by activated T cells. The biologic functions of IL-21 have not yet extensively studied. METHODS In the present study, we investigate the… CONTINUE READING
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