The Probability that Related Individuals Share Some Section of Genome Identical by Descent

@inproceedings{2003ThePT,
  title={The Probability that Related Individuals Share Some Section of Genome Identical by Descent},
  author={},
  year={2003}
}
  • Published 2003
A formal mathematical framework is presented for the study of linkage in man and the concept of chromosome pedigree is defined for both autosomes and X chromosomes. It is shown that, assuming no interference, all the crossover processes in the pedigree may be viewed jointly as a continuous-time Markov random walk on the vertices of a hypercube, the time parameter being map distance along the chromosome. The event that two individuals have a segment of chromosome in common, thus proving them to… CONTINUE READING
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