The Primary Cilium: Keeper of the Key to Cell Division

@article{Pan2007ThePC,
  title={The Primary Cilium: Keeper of the Key to Cell Division},
  author={Junmin Pan and William J Snell},
  journal={Cell},
  year={2007},
  volume={129},
  pages={1255-1257}
}
Assembly of the nonmotile primary cilium of vertebrate cells requires one of the centrioles of the centrosome. A cluster of new studies, including one in this issue of Cell by Pugacheva et al. (2007), reveal that ciliary assembly proteins influence cell-cycle progression and that a centrosomal "mitotic kinase" promotes ciliary disassembly. The link between the cell cycle and the primary cilium may reflect a requirement for liberation of the ciliary centriole to allow the centrosome to form the… Expand
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