The Prevalence of Individual Histopathologic Features Varies according to Autoantibody Status in Muscle Biopsies from Patients with Dermatomyositis.

@article{PinalFernandez2015ThePO,
  title={The Prevalence of Individual Histopathologic Features Varies according to Autoantibody Status in Muscle Biopsies from Patients with Dermatomyositis.},
  author={Iago Pinal-Fernandez and Livia A. Casciola-Rosen and Lisa Christopher-Stine and Andrea M. Corse and Andrew Mammen},
  journal={The Journal of rheumatology},
  year={2015},
  volume={42 8},
  pages={1448-54}
}
OBJECTIVE Individual dermatomyositis (DM)-associated autoantibodies are associated with distinct clinical phenotypes. This study was undertaken to explore the association of these autoantibodies with specific muscle biopsy features. METHODS DM subjects with a muscle biopsy reviewed at Johns Hopkins had sera screened for autoantibodies recognizing Mi-2, transcriptional intermediary factor 1-γ (TIF1-γ), NXP2, MDA5, Ro52, PM-Scl, and Jo1. We also included anti-Jo1–positive patients with… CONTINUE READING
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