The Prevalence of CYP2B6 Gene Polymorphisms in Malaria-endemic Population of Timor in East Nusa Tenggara Indonesia

@inproceedings{Hananta2018ThePO,
  title={The Prevalence of CYP2B6 Gene Polymorphisms in Malaria-endemic Population of Timor in East Nusa Tenggara Indonesia},
  author={Linawati Hananta and Indwiani Astuti and Ahmad Hamim Sadewa and Josephine Alice and Jontari Hutagalung and Mustofa},
  booktitle={Osong public health and research perspectives},
  year={2018}
}
Objectives The CYP2B6 is one of the most polymorphic CYP genes in humans that has the potential to modify the pharmacological and toxicological responses to clinically important drugs such as antimalarial artemisinin and its derivatives. The aim of the study was to determine the frequency of CYP2B6 polymorphisms in Timor malaria endemic area, East Nusa Tenggara, Indonesia where Artemisin-based Combination Therapy (ACT) has been used to treat uncomplicated malaria. Methods A total of 109… CONTINUE READING
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