The Presence of Disease-Associated Prion Protein in Skeletal Muscle of Cattle Infected with Classical Bovine Spongiform Encephalopathy

@inproceedings{Okada2014ThePO,
  title={The Presence of Disease-Associated Prion Protein in Skeletal Muscle of Cattle
Infected with Classical Bovine Spongiform Encephalopathy},
  author={Hiroyuki Okada and Kohtaro Miyazawa and Shigeo Fukuda and Yoshifumi Iwamaru and Morikazu Imamura and Kentaro Masujin and Yuichi Matsuura and Takashi Fujii and Kei Fujii and Soichi Kageyama and Miyako Yoshioka and Y. Murayama and Takashi Yokoyama},
  booktitle={The Journal of veterinary medical science},
  year={2014}
}
The aim of this study was to investigate the presence of disease-associated prion protein (PrP(Sc)) in the skeletal muscle of cattle infected with classical bovine spongiform encephalopathy (C-BSE). The study was carried out systematically in 12 different muscle samples from 43 (3 field and 40 experimental) cases of C-BSE; however, muscle spindles were not available in many of these cases. Therefore, analysis became restricted to a total of 31 muscles in 23 cattle. Even after this restriction… CONTINUE READING