The Predictive Value of HER2 in Breast Cancer
@article{Piccart2001ThePV, title={The Predictive Value of HER2 in Breast Cancer}, author={M. Piccart and C. Lohrisch and A. Di Leo and D. Larsimont}, journal={Oncology}, year={2001}, volume={61}, pages={73 - 82} }
Measurement of molecular markers predictive of response to therapy should enable more selective and effective utilization of anticancer agents. The predictive value of HER2 remains a complex and inconclusive subject. In metastatic breast cancer, HER2-positive, ER-positive patients can show responses to endocrine treatment, but experience shorter time to progression and survival than HER2-negative patients. In the adjuvant setting, weak, retrospective evidence suggests that tamoxifen is… CONTINUE READING
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