The Predictive Toxicology Evaluation Challenge

  title={The Predictive Toxicology Evaluation Challenge},
  author={Ashwin Srinivasan and Ross D. King and Stephen Muggleton and Michael J. E. Sternberg},
Can an AI program contribute to scientific discovery? An area where this gauntlet has been thrown is that of understanding the mechanisms of chemical carcinogenesis. One approach is to obtain Structure-Activity Relationships (SARs) relating molecular structure to cancerous activity. Vital to this are the rodent carcinogenicity tests conducted within the US National Toxicology Program by the National Institute of Environmental Health Sciences (NIEHS). This has resulted in a large database of… CONTINUE READING
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