The Power of Detecting Enriched Patterns: An HMM Approach

@article{Zhai2010ThePO,
  title={The Power of Detecting Enriched Patterns: An HMM Approach},
  author={Zhiyuan Zhai and Shih-Yen Ku and Yihui Luan and Gesine Reinert and Michael S. Waterman and Fengzhu Sun},
  journal={Journal of computational biology : a journal of computational molecular cell biology},
  year={2010},
  volume={17 4},
  pages={
          581-92
        }
}
The identification of binding sites of transcription factors (TF) and other regulatory regions, referred to as motifs, located in a set of molecular sequences is of fundamental importance in genomic research. Many computational and experimental approaches have been developed to locate motifs. The set of sequences of interest can be concatenated to form a long sequence of length n. One of the successful approaches for motif discovery is to identify statistically over- or under-represented… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

  • P. A. Jones
  • discovery. J. Bioinform. Comput. Biol
  • 2002
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…