The Potential of Moringa oleifera to Induce Cerebral Leptin mRNA Expression and to Attenuate Oxidative Stress, Cognitive and Motor Deficits, Depression- and Anxiety- Like Behavior in Experimental Obese Model

  title={The Potential of Moringa oleifera to Induce Cerebral Leptin mRNA Expression and to Attenuate Oxidative Stress, Cognitive and Motor Deficits, Depression- and Anxiety- Like Behavior in Experimental Obese Model},
  author={Asmaa Ahmed Mahmoud and Fateheya Mohamed Metwally and Hend Rashad and Hanaa H. Ahmed and Asmaa M Elfiky and Aboelfetoh Mohamed Abdalla},
  journal={Pharmaceutical and Clinical Research},
Moringa oleifera showed an evident role against obesity and leptin resistance. However, Moringa oleifera potential effects on alteration of moods, cognitive as well as motor deficits in obese animal model have not been evaluated in a mechanistic way. So, the aim of the current study is to examine the potential of Moringa oleifera to induce cerebral leptin mRNA expression, and consequently its effects on amelioration of behavioral and biochemical alterations in obese female rats. Ethanolic… 
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Leptin: A potential novel antidepressant
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Moringa oleifera offers a Multi-Mechanistic Approach for Management of Obesity in Rats
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