The Potential of Minocycline for Neuroprotection in Human Neurologic Disease

  title={The Potential of Minocycline for Neuroprotection in Human Neurologic Disease},
  author={D. Zemke and A. Majid},
  journal={Clinical Neuropharmacology},
  • D. Zemke, A. Majid
  • Published 2004
  • Medicine
  • Clinical Neuropharmacology
  • Minocycline is a member of the tetracycline class of molecules with broad-spectrum antibiotic activity. The unique properties of minocycline result in increased tissue distribution when compared with the other tetracyclines. Of particular interest is the ability of minocycline to diffuse into the central nervous system at clinically effective levels. Aside from its antimicrobial properties, minocycline has been found to have beneficial effects on inflammation, microglial activation, matrix… CONTINUE READING
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