The Potential of β-Hydroxy-β-Methylbutyrate as a New Strategy for the Management of Sarcopenia and Sarcopenic Obesity

@article{Rossi2017ThePO,
  title={The Potential of $\beta$-Hydroxy-$\beta$-Methylbutyrate as a New Strategy for the Management of Sarcopenia and Sarcopenic Obesity},
  author={Andrea P. Rossi and A D'Introno and Sofia Rubele and Cesare Caliari and Stefano Gattazzo and Elena Zoico and Gloria Mazzali and Francesco Fantin and Mauro Zamboni},
  journal={Drugs \& Aging},
  year={2017},
  volume={34},
  pages={833-840}
}
Sarcopenia is defined as an age-related loss of skeletal muscle mass and function and is recognized as a major clinical problem for older people. Essential amino acid supplementation, particularly β-hydroxy-β-methylbutyrate (HMB), a metabolite of leucine that is produced in skeletal muscle, has been evaluated in several studies as a nutritional approach to enhancing muscle protein synthesis in healthy or frail elderly subjects. Studies performed in in vitro conditions show that HMB may be… Expand
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