• Corpus ID: 12343234

The Potential for Somnambulism Associated with Gabapentin

  title={The Potential for Somnambulism Associated with Gabapentin},
  author={Jonathan R. Scarff},
Somnambulism, or sleepwalking, is a parasomnia occurring during Non-Rapid Eye Movement (NREM) sleep. It is defined as complex behaviors during slow-wave (or deep) sleep, with the person often having no recollection of these events upon waking.1 It is associated with several medications, including sedative-hypnotics, antipsychotics, antidepressants, lithium, stimulants, antihistamines, and anticonvulsants.2-9 Other risk factors include a history of sleepwalking in a first-degree relative, sleep… 


Sleepwalking in four patients treated with quetiapine.
Sleepwalking (SW), also known as somnambulism, is characterized by episodes of complex motor behavior initiated during sleep, including rising from bed and walking about, and is likely to dissipate in adolescence.
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There is clearly a cause-and-effect relationship between the treatment of higher-dosage mirtazapine and development of somnambulism, which might be related to the different affinities to 5-hydroxytryptamine 2 (5-HT(2)) and H(1) receptors at different dosages of mirtzapine, which explain the patient experiencing sleepwalking episodes exclusively at higher doses of mIRTazapines.
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An unusual adverse effect of topiramate on sleep in a patient with migraine is presented, which is more common in children than in other patients with migraine.
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The clinical presentation and polysomnography of prepubertal children with repetitive sleep terrors and sleepwalking are evaluated, to compare them with a control group, and to evaluate the treatment of associated sleep disorders.
Dyssomnias and Parasomnias in Early Childhood
There is a high prevalence of night wakings and sleep-onset difficulties in preschool children and Parasomnias are highly prevalent in early childhood and are associated with separation anxiety, however, they have little impact on sleep duration.
Effects of epilepsy treatments on sleep architecture and daytime sleepiness: An evidence‐based review of objective sleep metrics
A systemic literature review is performed to evaluate the effect of antiepileptic drugs and nondrug treatments for epilepsy on sleep architecture to help better understand treatment effects, especially in patients with epilepsy and sleep problems.