The Potential and Hurdles of Targeted Alpha Therapy – Clinical Trials and Beyond

@inproceedings{Elgqvist2013ThePA,
  title={The Potential and Hurdles of Targeted Alpha Therapy – Clinical Trials and Beyond},
  author={J{\"o}rgen Elgqvist and Sofia H L Frost and Jean-Pierre Pouget and Per Arne Albertsson},
  booktitle={Front. Oncol.},
  year={2013}
}
This article presents a general discussion on what has been achieved so far and on the possible future developments of targeted alpha (α)-particle therapy (TAT). Clinical applications and potential benefits of TAT are addressed as well as the drawbacks, such as the limited availability of relevant radionuclides. Alpha-particles have a particular advantage in targeted therapy because of their high potency and specificity. These features are due to their densely ionizing track structure and short… CONTINUE READING