The Potential Value and Toxicity of Chromium Picolinate as a Nutritional Supplement, Weight Loss Agent and Muscle Development Agent

@article{Vincent2003ThePV,
  title={The Potential Value and Toxicity of Chromium Picolinate as a Nutritional Supplement, Weight Loss Agent and Muscle Development Agent},
  author={John B. Vincent},
  journal={Sports Medicine},
  year={2003},
  volume={33},
  pages={213-230}
}
The element chromium apparently has a role in maintaining proper carbohydrate and lipid metabolism in mammals. As this role probably involves potentiation of insulin signalling, chromium dietary supplementation has been postulated to potentially have effects on body composition, including reducing fat mass and increasing lean body mass. Because the supplement is absorbed better than dietary chromium, most studies have focused on the use of chromium picolinate [Cr(pic)3]. Cr(pic)3 has been… 
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A–Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance Part 9
TLDR
Part 9 of the series on dietary supplements includes summaries of three products which address these interests among other claimed benefits: choline bitartrate, chromium picolinate and cissus quandrangularis (CQ).
Recent advances in the nutritional biochemistry of trivalent chromium
  • J. Vincent
  • Biology
    Proceedings of the Nutrition Society
  • 2004
TLDR
A mechanism for the action of chromodulin has recently been proposed and can serve as a potential framework for further studies to test the role of Cr in metabolism, as the molecule has been found to bind to activated insulin receptor, stimulating its kinase activity.
A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women
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Results indicate that Phaseolus vulgaris extract produces significant decrement in body weight and suggest decrements in fat mass in the face of maintained lean body mass and indicate the use of natural weight loss supplements could aid in the struggle against obesity.
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TLDR
Chromium is only a small part of the puzzle in the control of weight loss and body composition, and its effects, if present, will be small compared with those of exercise and a well-balanced diet.
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TLDR
Recently, chromium has been touted as an agent for increasing lean body mass and decreasing percent body fat and the various studies that have been conducted to investigate the relationship of chromium with exercise and body composition are reviewed.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
Observations show that chromium picolinate is efficacious in lowering blood lipids in humans.
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