The Potential Role of DNA Methylation in Abdominal Aortic Aneurysms

  title={The Potential Role of DNA Methylation in Abdominal Aortic Aneurysms},
  author={Evan J Ryer and Kaitryn E. Ronning and Robert Erdman and Charles M. Schworer and James R. Elmore and Thomas C. Peeler and Christopher D. Nevius and John H. Lillvis and Robert P. Garvin and David P. Franklin and Helena Kuivaniemi and Gerard Tromp and Jonathan Golledge and Joseph Vaughan Moxon},
  booktitle={International journal of molecular sciences},
Abdominal aortic aneurysm (AAA) is a complex disorder that has a significant impact on the aging population. While both genetic and environmental risk factors have been implicated in AAA formation, the precise genetic markers involved and the factors influencing their expression remain an area of ongoing investigation. DNA methylation has been previously used to study gene silencing in other inflammatory disorders and since AAA has an extensive inflammatory component, we sought to examine the… CONTINUE READING
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