The Potential Benefits of Red Beetroot Supplementation in Health and Disease

@article{Clifford2015ThePB,
  title={The Potential Benefits of Red Beetroot Supplementation in Health and Disease},
  author={Tom Clifford and Glyn Howatson and Daniel J. West and Emma J. Stevenson},
  journal={Nutrients},
  year={2015},
  volume={7},
  pages={2801 - 2822}
}
In recent years there has been a growing interest in the biological activity of red beetroot (Beta vulgaris rubra) and its potential utility as a health promoting and disease preventing functional food. As a source of nitrate, beetroot ingestion provides a natural means of increasing in vivo nitric oxide (NO) availability and has emerged as a potential strategy to prevent and manage pathologies associated with diminished NO bioavailability, notably hypertension and endothelial function… 
Functional properties of beetroot (Beta vulgaris) in management of cardio-metabolic diseases
TLDR
It is shown that the persistent consumption of beetroot juice effectively postpones the postprandial glycemic response and decreases the blood glucose peak.
Biological effects of red beetroot and betalains: A review.
TLDR
This review summarizes findings in the literature and shows the therapeutic potential of red beetroot and its active compounds (betalains) as promising alternatives for supplemental therapies in multiple diseases.
Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
TLDR
The aim of this review article is to analyze the current knowledge regarding the benefits related to the consumption of beetroot and derived food-supplements and focus on nitrate and betalains, considered to be the major bioactive compounds present in beetroot, and thus in the derived dietary supplements.
Beetroot as a Potential Functional Food for Cancer Chemoprevention, a Narrative Review
TLDR
The main aim of this narrative review is to discuss beetroot’s nutrient composition, current studies on its potential utility in chemoprevention and cancer-related fatigue or treatment-related side effects such as cardiotoxicity, and the related research gaps in this area.
Red Beetroot: Composition and Health Effects - A Review
Red beetroot belongs to the Beta L. genus, the Betoideae subfamily of the goosefoot family (Amaranthaceae). Beetroot (Beta vulgaris L.) is a vegetable consumed worldwide due to its high content of
Evaluation of Functional Properties of Beetroot Powder (Beta vulgaris) and its Suitability in Developing a Candy by Incorporate
Beetroot, that is extensively cultivated in cool weather conditions at the temperature ranges from 18-21  C. It found to be a potentially therapeutic agent with good source of bioactive principle in
Red Beetroot Betalains: Perspectives on Extraction, Processing, and Potential Health Benefits.
TLDR
The effective extraction and processing methods of betalains from red beetroot were emphatically reviewed and a variety of recently reported bioactivities of beetroot betalain were also summarized.
Investigation of Mineral and Vitamin C Contents in Different Parts of Beetroots (Beta vulgaris L.)
Due to the increasing popularity of today’s health-conscious culture, beetroot plays an increasingly important role in a healthy, varied diet. While it contains vitamins B1, B2, B6, P, as well as
Beetroot juice attenuates glycaemic response in healthy volunteers
TLDR
The consumption of beetroot juice in comparison to the sugar matched control drink reduced blood glucose levels significantly after 15, 30, 90 and 180 min, demonstrating a reduction in peak and early phase as well as a delay in glycaemic response.
Use of Red Beet (Beta vulgaris L.) for Antimicrobial Applications—a Critical Review
TLDR
The findings from recent studies quantifying phytochemical antioxidants in red beet in comparison with other natural sources are summarized and critically examine the current research where the antimicrobial potential of red beet extract has investigated, highlighting the associated challenges and limitations.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 106 REFERENCES
Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats.
TLDR
The results confirm the protective effect of beetroot juice against oxidative damage shown in previous studies and indicate that metabolic alterations induced by beetroot feeding may protect against liver damage.
Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway.
  • S. Lidder, A. Webb
  • Chemistry, Medicine
    British journal of clinical pharmacology
  • 2013
TLDR
The Nitrate 'Veg-Table' with 'Nitrate Units' is developed to achieve a nitrate intake that is likely to be sufficient to derive benefit, but also to minimize the risk of potential side effects from excessive ingestion, given the current available evidence.
Nutritional and functional potential of Beta vulgaris cicla and rubra.
TLDR
The opportunity to take advantage of the large availability of this crop for purification of chemopreventive molecules to be used in functional foods and nutraceutical products is suggested.
In vitro effects of beetroot juice and chips on oxidative metabolism and apoptosis in neutrophils from obese individuals
TLDR
These natural products (in both the liquid and solid state) have antioxidant and antiinflammatory capacity, and could be an important adjunct in the treatment of obesity.
In vivo and in vitro antioxidant effects of beetroot pomace extracts
Abstract Beetroot pomace, processing by-product from food industry, was investigated in this work. Free radical scavenging activity of Detroit, Cardeal-F1, Egyptian, Bicor and Kestrel beetroot pomace
In vitro Effects of Beet Root Juice on Stimulated and Unstimulated Peripheral Blood Mononuclear Cells
TLDR
Data show that beetroot extract is able to counteract pro-inflammatory cascades in peripheral blood mononuclear cells, and beneficial effect of beetroot extracts may relate to this anti-inflammatory capacity.
Effects of a beetroot juice with high neobetanin content on the early-phase insulin response in healthy volunteers
TLDR
Betalains, polyphenols and dietary nitrate found in the beetroot juice may each contribute to the observed differences in the postprandial insulin concentration.
Antioxidant effects of resveratrol and other stilbene derivatives on oxidative stress and *NO bioavailability: Potential benefits to cardiovascular diseases.
TLDR
This review presents the latest findings on the molecular effects of resveratrol and other stilbene derivatives on the various actors that modulate *NO bioavailability during oxidative stress.
Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines
TLDR
The results indicated that an overall positive reduction in drug concentration was achieved by D when combined with B in its cytotoxicity profile in the three human cancer cells tested.
Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals.
  • R. Liu
  • Biology, Medicine
    The American journal of clinical nutrition
  • 2003
TLDR
It is proposed that the additive and synergistic effects of phytochemicals in fruit and vegetables are responsible for their potent antioxidant and anticancer activities, and that the benefit of a diet rich in Fruit and vegetables is attributed to the complex mixture of phydochemicals present in whole foods.
...
1
2
3
4
5
...