The Postsynaptic Localization of the Glycine Receptor-Associated Protein Gephyrin Is Regulated by the Cytoskeleton

@inproceedings{J2003ThePL,
  title={The Postsynaptic Localization of the Glycine Receptor-Associated Protein Gephyrin Is Regulated by the Cytoskeleton},
  author={J.... and Kirscha},
  year={2003}
}
  • J...., Kirscha
  • Published 2003
The mechanisms underlying the postsynaptic localization of neurotransmitter receptors are poorly understood. Recently, the peripheral membrane protein gephyrin has been shown to be essential for the formation of inhibitory glytine receptor clusters in cultured rat spinal cord neurons. In vitro gephyrin binds with high affinity to polymerized tubulin. Here, the interaction of gephyrin with different components of the cytoskeleton was investigated in primary cultures of rat spinal neurons. After… CONTINUE READING
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