The Polygenomic Organism

  title={The Polygenomic Organism},
  author={John Dupr{\'e}},
  journal={The Sociological Review},
  pages={19 - 31}
  • J. Dupré
  • Published 1 May 2010
  • Psychology
  • The Sociological Review
Research supported by the Economic and Social Research Council (ESRC) and the Arts and Humanities Research Council (AHRC). 

Experimenting in the Biosocial: The Strange Case of Twin Research

In this chapter, I explore how twin research has been used to prove and disprove divisions between biology and environment. The history of using twins in biomedical research has lessons for

The Problem of Biological Individuality

There is a real problem of biological individuality, and an urgent need to arbitrate among the current plethora of solutions to it.

Symbiosis, selection, and individuality

It is explained how two distinct foundational accounts of the process of natural selection give rise to competing views about evolutionary individuality.

Unstable Bodies: Biosocial Perspectives on Human Variation

Biological and physical anthropologists have tended to see the study of human variation and the material body as the defining elements of their subdiscipline(s). Generally, sociologists and social

Marked ‘h’ for human: Chimeric life and the politics of the human

Drawing on fieldwork conducted at a stem cell laboratory and farm animal research institute, the paper argues that meanings of the human become elusive and unknown when intertwined with chimeric life.

The Trustworthiness Deficit in Postgenomic Research on Human Intelligence.

In the past, work on racial and ethnic variation in brain and behavior was marginalized within genetics. Against the backdrop of genetics' eugenic legacy, wide consensus held such research to be both

Coding the Self: The Infopolitics and Biopolitics of Genetic Sciences.

The infopolitical model offers a way of understanding how ethically salient and politically fraught conceptual assumptions can be embedded in informational architectures such as algorithms and the formats (or data structures) upon which they rely.

Toward a Living Architecture?

Author(s): Cogdell, Christina | Abstract: Toward a Living Architecture? examines the emerging field of generative architecture and its nexus with computation, biology, and complexity. Based on

Sociology in an Age of Genomic Instability: Copy Number Variation, Somatic Mosaicism, and the Fallen Genome

This study analyzes the rise of genome instability in the life sciences and traces the problematic of instability as it relates to the sociology of health and identifies practical and conceptual implications of genomic instability for life scientists and helps sociologists delineate new approaches to the study of genomics in the post-genomic era.

Strata of the political: epigenetic and microbial imaginaries in post-apartheid Cape Town

: The epigenetic and microbiomic imaginaries that animate public health discourse on perinatal nutrition and the infant gut in South Africa offer a case study through which to reconsider the



What does the British public think about human–animal hybrid embryos?

  • D. Jones
  • Biology
    Journal of Medical Ethics
  • 2009
In the recent UK debate on the Human Fertilisation and Embryology Bill, there have been conflicting claims about the extent of public support for, or opposition to, human–animal hybrids.

Genetic Information: A Metaphor in Search of a Theory

It is argued that on any definition of information the view that development is the expression of genetic information is misleading and that developmental biology is concerned with teleosemantic information.

Resurrecting Biological Essentialism*

The article defends the doctrine that Linnaean taxa, including species, have essences that are, at least partly, underlying intrinsic, mostly genetic, properties. The consensus among philosophers of

Does gene dosage really matter?

Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals, but in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical.

Disputed maternity leading to identification of tetragametic chimerism.

A phenotypically normal woman who was found to have tetragametic chimerism after histocompatibility testing of family members suggested that she was not the biologic mother of two of her three children is described.

The Concept of Information in Biology

In biology, the use of informational terms implies intentionality, in that both the form of the signal, and the response to it, have evolved by selection.

Noise in Gene Expression: Origins, Consequences, and Control

Noise terminology is summarized and comment on recent investigations into the sources, consequences, and control of noise in gene expression are commented on.

Stress During Gestation Alters Postpartum Maternal Care and the Development of the Offspring in a Rodent Model

Size doesn’t matter: towards a more inclusive philosophy of biology

It is suggested that taking more notice of microbes will transform some of the philosophy of biology’s standard ideas on ontology, evolution, taxonomy and biodiversity and break down conventional thinking that microbes are solely or primarily single-celled organisms.

Diagnosis of freemartinism in cattle: the need for clinical and cytogenic evaluation.

It is proposed that obvious freemartins be identified by use of the vaginal-length test and that the remaining clinically questionable calves be differentiated cytogenetically, to prevent unnecessary economic losses and preserve important genetic material.