The Polycystic Ovary Syndrome and recent human evolution

@article{Corbett2013ThePO,
  title={The Polycystic Ovary Syndrome and recent human evolution},
  author={S. Corbett and L. Morin-Papunen},
  journal={Molecular and Cellular Endocrinology},
  year={2013},
  volume={373},
  pages={39-50}
}
The Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder characterised both by reproductive and metabolic disturbance, and is the most common cause globally of ovarian infertility. It is also a familial polygenic condition, linked genetically to both Type 2 diabetes and the metabolic syndrome. The striking evolutionary paradox of this prominent genetically-based condition, which impairs fertility, is that not only should it have diminished in prevalence, but it should have done so… Expand
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