The Polo-like kinase Plx1 is a component of the MPF amplification loop at the G2/M-phase transition of the cell cycle in Xenopus eggs.

Abstract

We have investigated whether Plx1, a kinase recently shown to phosphorylate cdc25c in vitro, is required for activation of cdc25c at the G2/M-phase transition of the cell cycle in Xenopus. Using immunodepletion or the mere addition of an antibody against the C terminus of Plx1, which suppressed its activation (not its activity) at G2/M, we show that Plx1… (More)

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@article{Abrieu1998ThePK, title={The Polo-like kinase Plx1 is a component of the MPF amplification loop at the G2/M-phase transition of the cell cycle in Xenopus eggs.}, author={Ariane Abrieu and Thierry Brassac and Simon Galas and D. Fisher and J. Claude Labb{\'e} and Marcel Dor{\'e}e}, journal={Journal of cell science}, year={1998}, volume={111 ( Pt 12)}, pages={1751-7} }