The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites.

@article{Moreira2008ThePT,
  title={The Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites.},
  author={Cristina K Moreira and Thomas J. Templeton and Catherine Lavazec and Rhian E. Hayward and Charlotte V. Hobbs and Hans Kroeze and Chris J Janse and Andrew P Waters and Photini Sinnis and Alida Coppi},
  journal={Cellular microbiology},
  year={2008},
  volume={10 7},
  pages={1505-16}
}
In the apicomplexan protozoans motility and cell invasion are mediated by the TRAP/MIC2 family of transmembrane proteins, members of which link extracellular adhesion to the intracellular actomyosin motor complex. Here we characterize a new member of the TRAP/MIC2 family, named TRAP-Like Protein (TLP), that is highly conserved within the Plasmodium genus. Similar to the Plasmodium sporozoite protein, TRAP, and the ookinete protein, CTRP, TLP possesses an extracellular domain architecture that… CONTINUE READING
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