The Placenta Harbors a Unique Microbiome

@article{Aagaard2014ThePH,
  title={The Placenta Harbors a Unique Microbiome},
  author={Kjersti Aagaard and Jun Ma and Kathleen M Antony and Radhika S Ganu and Joseph F Petrosino and James Versalovic},
  journal={Science Translational Medicine},
  year={2014},
  volume={6},
  pages={237ra65-237ra65}
}
Humans and their microbiomes have coevolved as a physiologic community composed of distinct body site niches with metabolic and antigenic diversity. The placental microbiome has not been robustly interrogated, despite recent demonstrations of intracellular bacteria with diverse metabolic and immune regulatory functions. A population-based cohort of placental specimens collected under sterile conditions from 320 subjects with extensive clinical data was established for comparative 16S ribosomal… CONTINUE READING
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