The Pivotal Role of 5-Lipoxygenase-Derived LTB4 in Controlling Pulmonary Paracoccidioidomycosis

@inproceedings{Santos2013ThePR,
  title={The Pivotal Role of 5-Lipoxygenase-Derived LTB4 in Controlling Pulmonary Paracoccidioidomycosis},
  author={Patr{\'i}cia Campi Santos and Daniel de Assis Santos and Lucas S Ribeiro and Caio Tavares Fagundes and Talles Prosperi de Paula and Thiago Vin{\'i}cius {\'A}vila and Ludmila de Matos Baltazar and Mila F M Madeira and Rosana de Carvalho Cruz and Ana Carolina Fialho Dias and Fabiana Sim{\~a}o Machado and Mauro M Teixeira and Patr{\'i}cia Silva Cisalpino and Danielle G Souza},
  booktitle={PLoS neglected tropical diseases},
  year={2013}
}
Leukotrienes (LTs) produced from arachidonic acid by the action of 5-lipoxygenase (5-LO) are classical mediators of inflammatory responses. However, studies published in the literature regarding these mediators are contradictory and it remains uncertain whether these lipid mediators play a role in host defense against the fungal pathogen Paracoccidioides… CONTINUE READING