The Pilin N-terminal Domain Maintains Neisseria gonorrhoeae Transformation Competence during Pilus Phase Variation

Abstract

The obligate human pathogen Neisseria gonorrhoeae is the sole aetiologic agent of the sexually transmitted infection, gonorrhea. Required for gonococcal infection, Type IV pili (Tfp) mediate many functions including adherence, twitching motility, defense against neutrophil killing, and natural transformation. Critical for immune escape, the gonococcal Tfp… (More)
DOI: 10.1371/journal.pgen.1006069

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@inproceedings{Obergfell2016ThePN, title={The Pilin N-terminal Domain Maintains Neisseria gonorrhoeae Transformation Competence during Pilus Phase Variation}, author={Kyle P Obergfell and H Steven Seifert}, booktitle={PLoS genetics}, year={2016} }