The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease

@inproceedings{Luz2014ThePR,
  title={The Physiopathological Role of IL-33: New Highlights in Bone Biology and a Proposed Role in Periodontal Disease},
  author={Felipe Andr{\'e}s Cordero da Luz and Ana Paula Lima Oliveira and Daniella Borges and Paula Cristina Br{\'i}gido and Marcelo Jos{\'e} Barbosa Silva},
  booktitle={Mediators of inflammation},
  year={2014}
}
Interleukin-33 (IL-33) is a recently described member of the IL-1 family. IL-33 acts as an alarmin, chemoattractant, and nuclear factor. ST2, a member of the Toll-like receptor/IL-1R superfamily, the receptor of IL-33, triggers a plethora of downstream effectors and leads the activation of NFK-B, leading the expression of several genes. IL-33 and ST2 are expressed in the majority of cell types, and the IL-33/ST2 axis has a role in immune response, bone homeostasis, and osteoclastogenesis… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Similar Papers

Loading similar papers…