The Physiology, Signaling, and Pharmacology of Dopamine Receptors

  title={The Physiology, Signaling, and Pharmacology of Dopamine Receptors},
  author={Jean-Martin Beaulieu and Raul R. Gainetdinov},
  journal={Pharmacological Reviews},
  pages={182 - 217}
G protein-coupled dopamine receptors (D1, D2, D3, D4, and D5) mediate all of the physiological functions of the catecholaminergic neurotransmitter dopamine, ranging from voluntary movement and reward to hormonal regulation and hypertension. Pharmacological agents targeting dopaminergic neurotransmission have been clinically used in the management of several neurological and psychiatric disorders, including Parkinson's disease, schizophrenia, bipolar disorder, Huntington's disease, attention… 

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