The PhoB regulatory system modulates biofilm formation and stress response in El Tor biotype Vibrio cholerae.

@article{Sultan2010ThePR,
  title={The PhoB regulatory system modulates biofilm formation and stress response in El Tor biotype Vibrio cholerae.},
  author={Syed Zafar Sultan and Rosilene Agra da Silva and Jorge A Benitez},
  journal={FEMS microbiology letters},
  year={2010},
  volume={302 1},
  pages={
          22-31
        }
}
The PhoBR regulatory system is required for the induction of multiple genes under conditions of phosphate limitation. Here, we examine the role of PhoB in biofilm formation and environmental stress response in Vibrio cholerae of the El Tor biotype. Deletion of phoB or hapR enhanced biofilm formation in a phosphate-limited medium. Planktonic and redispersed biofilm cells of the DeltaphoB mutant did not differ from wild type for the expression of HapR, suggesting that PhoB negatively affects… CONTINUE READING
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