The Philosophy and History of Molecular Biology: New Perspectives

  title={The Philosophy and History of Molecular Biology: New Perspectives},
  author={Sahotra Sarkar},
Editor's Foreword S. Sarkar. What the Double Helix (1953) Has Meant for Basic Biomedical Science: A Personal Commentary J. Lederberg. Theory Structure and Knowledge Representation in Molecular Biology K.F. Schaffner. Redrawing the Boundaries of Molecular Biology: The Case of Photosynthesis D.T. Zallen. Underappreciated Pathways Toward Molecular Genetics as Illustrated by Jean Brachet's Cytochemical Embryology R.M. Burian. Life as Technology: Representing, Interventing, and Molecularizing L.E… 

What history tells us XVI. A third pillar for molecular biology: Molecular embryology

It is argued that molecular embryology was more than a simple contributor to the development of the molecular paradigm, and was a full partner, a third pillar of molecular biology, with a different conception of molecular organization, and different experimental systems.

Genetic Information in the Age of DNA Sequencing

It is argued that DNA sequencing, rather than changing the meaning of genetic information, transformed the possibilities of what could be achieved with this concept and directed it to large-scale enterprises such as the Human Genome Project.

Macromolecules, Genomes and Ourselves

The requirement for a systems view of life in order to construct new models for the era of post-genomic biomedicine is considered and the case that such models are metaphoric constructions is considered.

Embracing complexity: Organicism for the 21st century

  • S. GilbertS. Sarkar
  • Art
    Developmental dynamics : an official publication of the American Association of Anatomists
  • 2000
This essay attempts to define organicism, provide a brief history of its importance to experimental embryology, outline some sociologically based reasons for its decline, and document its value in contemporary developmental biology.

A New Insight into Sanger’s Development of Sequencing: From Proteins to DNA, 1943–1977

It is claimed that sequencing shifted from the working procedures of organic chemistry to those of the emergent molecular biology, which leads to a reappraisal of current STS debates on bioinformatics, biotechnology and biomedicine.

Information in the Biological Sciences

This chapter considers the debate regarding the reality and nature of bioinformation, arguing that bioinformation is best understood as a relationship between and/or among entities, and shows how bioinformation relates to other concepts such as entropy, order, organization, complexity, and knowledge.

Philosophy of Biology: About the Fossilization of Disciplines and Other Embryonic Thoughts

This paper focuses on a running dispute between Werner Callebaut’s naturalistic view and Filip Kolen and Gertrudis Van de Vijver’s transcendentalist view on the nature of philosophy of biology and

The rise and fall of the idea of genetic information (1948-2006)

It is suggested that the concept of DNA as information reached a climax with the proposal of the Human Genome Project (HGP), but is currently facing a crisis coinciding with the questioning of the information society.