The Pfam protein families database

  title={The Pfam protein families database},
  author={Alex Bateman and Lachlan James M. Coin and Richard Durbin and Robert D. Finn and Volker Hollich and Sam Griffiths-Jones and Ajay Khanna and Mhairi Marshall and Simon Moxon and Erik L. L. Sonnhammer and David J. Studholme and Corin Yeats and Sean R. Eddy},
  journal={Nucleic acids research},
  volume={28 1},
Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the WWW in the UK at, in Sweden at and in the US at The latest version (4.3) of Pfam contains 1815 families. These Pfam families match 63% of proteins in SWISS-PROT 37 and TrEMBL 9. For complete genomes Pfam currently matches up to half of the proteins. Genomic DNA can be directly… CONTINUE READING
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