The Pax2/5/8 gene egl-38 coordinates organogenesis of the C. elegans egg-laying system.

@article{Rajakumar2007ThePG,
  title={The Pax2/5/8 gene egl-38 coordinates organogenesis of the C. elegans egg-laying system.},
  author={Vandana Rajakumar and Helen M. Chamberlin},
  journal={Developmental biology},
  year={2007},
  volume={301 1},
  pages={240-53}
}
Organogenesis requires coordinated development between different tissues and cells. The Pax family of transcription factors coordinates multiple developmental events in organs including the kidney, thyroid and the eye. Studying Pax factors in different organisms should identify unifying characteristics of organ development with implications to both development and disease. Here we investigate the function of the Pax2/5/8 transcription factor EGL-38 in coordinating development of the C. elegans… CONTINUE READING