The Pathophysiologic Roles of TRPM7 Channel

@inproceedings{Park2014ThePR,
  title={The Pathophysiologic Roles of TRPM7 Channel},
  author={Hyun Young Park and Chansik Hong and Byung Joo Kim and Insuk So},
  booktitle={The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology},
  year={2014}
}
Transient receptor potential melastatin 7 (TRPM7) is a member of the melastatin-related subfamily and contains a channel and a kinase domain. TRPM7 is known to be associated with cell proliferation, survival, and development. It is ubiquitously expressed, highly permeable to Mg(2+) and Ca(2+), and its channel activity is negatively regulated by free Mg(2+) and Mg-complexed nucleotides. Recent studies have investigated the relationships between TRPM7 and a number of diseases. TRPM7 regulates… CONTINUE READING

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