The Pathomechanics of Gait in Duchenne Muscular Dystrophy

  title={The Pathomechanics of Gait in Duchenne Muscular Dystrophy},
  author={D H Sutherland and Richard A. Olshen and Leslie W. Cooper and Marilynn P. Wyatt and Judy Leach and Scott J. Mubarak and Paul Schultz},
  journal={Developmental Medicine \& Child Neurology},
Forty‐six separate gait studies were analysed for 21 ambulatory patients with Duchenne muscular dystrophy. Three groups were defined on the basis of significant gait variables: early, transitional and late. Disease progression can be predicted with 91 per cent accuracy by three gait variables: cadence, dorsiflexion in swing, and anterior pelvic tilt. 
Gait assessment with solesound instrumented footwear in spinal muscular atrophy
Gait impairment is common in spinal muscular atrophy (SMA) and is described using clinical assessments and instrumented walkways. Continuous over‐ground walking has not been studied.
Changes in center of gravity in boys with duchenne muscular dystrophy
The purpose of this study was to monitor changes in the locus of the center of gravity and the range and frequency of sway and to evaluate the effect of orthotic application in an attempt to obtain information that would assist further development of orthoses.
Gait Analysis in Pediatric Rehabilitation
Gait analysis has been successfully applied in the evaluation and treatment of cerebral palsy, myelomeningocele, muscular dystrophy, and limb-deficient states.
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3D Gait Analysis gives objective and quantitative information about the gait pattern and the deviations due to muscular situation of DMD subjects; being a single moment evaluation, it is otherwise unable to unravel changes only detectable through serial analysis during the time course of the disease and, if any, due to the treatment.
Ankle bracing practices in ambulatory, corticosteroid‐naive boys with Duchenne muscular dystrophy
Strategies to maintain ankle range of motion are employed, but little evidence exists to support these approaches and limited information is available concerning current practice.
Evaluation of gait in Duchenne Muscular Dystrophy: Relation of 3D gait analysis to clinical assessment
3D gait analysis may provide useful objective and accurate parameters reflecting the functional ability of individuals with DMD, and suggest that 3D optoelectronic system could provide elements useful for the functional evaluation of patients with D MD.
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When muscular dystrophy leads to more disability the myopathic patients tended to change from the normal plantigrade gait pattern to an infantile digitigrade-like pattern with a decrease of the tibialis anterior muscle work.
Gait Assessment in Children With Duchenne Muscular Dystrophy During Long-Distance Walking
The authors noticed significantly higher values both for cadence and stride velocity, as well as improved trunk smoothness in the mild versus moderate group, when the group of patients was divided into mild and moderate based on the Motor Function Measure.
Classification of the Gait Patterns of Boys With Duchenne Muscular Dystrophy and Their Relationship to Function
In boys with Duchenne muscular dystrophy, gait pattern deviations are related to function, which can provide further insight into the understanding of disease progression and treatment options to enhance function and maintain ambulation.
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Two siblings with nemaline myopathy were analysed and patients developed a serial of postural adaptations and no correlation between muscle strength and functional level was found.


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In a study of 27 patients with progressive muscular dystrophy of childhood, it was found that duration of ambulation from onset of symptoms could be increased from an average of 4.4 yr to 8.7 yr by a
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1. Fifteen of seventeen patients with childhood muscular dystrophy who had ceased walking because of muscle weakness were able to walk independently again after correction of contractures and fitting
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The purpose of this presentation is to outline measures that are useful in the managensenst of dvstroplsic patienits.
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Walking and running on the level involves external mechanical work, even when speed averaged over a complete stride remains constant. This work must be performed by the muscles to accelerate and/or