The Pain of Sleep Loss: A Brain Characterization in Humans

@article{Krause2019ThePO,
  title={The Pain of Sleep Loss: A Brain Characterization in Humans},
  author={Adam J. Krause and Aric A. Prather and Tor D. Wager and Martin A. Lindquist and Matthew P. Walker},
  journal={The Journal of Neuroscience},
  year={2019},
  volume={39},
  pages={2291 - 2300}
}
Sleep loss increases the experience of pain. However, the brain mechanisms underlying altered pain processing following sleep deprivation are unknown. Moreover, it remains unclear whether ecologically modest night-to-night changes in sleep, within an individual, confer consequential day-to-day changes in experienced pain. Here, we demonstrate that acute sleep deprivation amplifies pain reactivity within human (male and female) primary somatosensory cortex yet blunts pain reactivity in higher… Expand
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