The Pain of Sleep Loss: A Brain Characterization in Humans

@article{Krause2019ThePO,
  title={The Pain of Sleep Loss: A Brain Characterization in Humans},
  author={Adam J Krause and A. Prather and T. Wager and M. Lindquist and M. Walker},
  journal={The Journal of Neuroscience},
  year={2019},
  volume={39},
  pages={2291 - 2300}
}
  • Adam J Krause, A. Prather, +2 authors M. Walker
  • Published 2019
  • Medicine
  • The Journal of Neuroscience
  • Sleep loss increases the experience of pain. However, the brain mechanisms underlying altered pain processing following sleep deprivation are unknown. Moreover, it remains unclear whether ecologically modest night-to-night changes in sleep, within an individual, confer consequential day-to-day changes in experienced pain. Here, we demonstrate that acute sleep deprivation amplifies pain reactivity within human (male and female) primary somatosensory cortex yet blunts pain reactivity in higher… CONTINUE READING
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    References

    SHOWING 1-10 OF 96 REFERENCES
    The impact of sleep deprivation on food desire in the human brain
    • 175
    • PDF
    Sleep deprivation and pain perception.
    • 442
    • PDF
    The Cerebral Signature for Pain Perception and Its Modulation
    • 1,284
    • PDF
    The human emotional brain without sleep — a prefrontal amygdala disconnect
    • 807
    • PDF
    Sleep Deprivation Impairs the Human Central and Peripheral Nervous System Discrimination of Social Threat
    • 54
    • PDF
    Activation of Corticostriatal Circuitry Relieves Chronic Neuropathic Pain
    • 131
    • PDF
    Self-reported sleep duration associated with distraction analgesia, hyperemia, and secondary hyperalgesia in the heat-capsaicin nociceptive model.
    • 29
    Sleep Deprivation Amplifies Reactivity of Brain Reward Networks, Biasing the Appraisal of Positive Emotional Experiences
    • 322
    • PDF