The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila.

@article{Wang2016ThePS,
  title={The PSI-U1 snRNP interaction regulates male mating behavior in Drosophila.},
  author={Qingqing Wang and J Matthew Taliaferro and Ugne Klibaite and Val{\'e}rie Hilgers and Joshua W. Shaevitz and Donald C. Rio},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2016},
  volume={113 19},
  pages={5269-74}
}
Alternative pre-mRNA splicing (AS) is a critical regulatory mechanism that operates extensively in the nervous system to produce diverse protein isoforms. Fruitless AS isoforms have been shown to influence male courtship behavior, but the underlying mechanisms are unknown. Using genome-wide approaches and quantitative behavioral assays, we show that the P… CONTINUE READING