The PROTICdb database for 2-DE proteomics.

@article{Langella2007ThePD,
  title={The PROTICdb database for 2-DE proteomics.},
  author={Olivier Langella and Michel Zivy and Johann Joets},
  journal={Methods in molecular biology},
  year={2007},
  volume={355},
  pages={
          279-303
        }
}
PROTICdb is a web-based database mainly designed to store and analyze plant proteome data obtained by 2D polyacrylamide gel electrophoresis (2D PAGE) and mass spectrometry (MS). The goals of PROTICdb are (1) to store, track, and query information related to proteomic experiments, i.e., from tissue sampling to protein identification and quantitative measurements; and (2) to integrate information from the user's own expertise and other sources into a knowledge base, used to support data… 
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References

SHOWING 1-5 OF 5 REFERENCES
PROTICdb: A web‐based application to store, track, query, and compare plant proteome data
PROTICdb is a web‐based application, mainly designed to store and analyze plant proteome data obtained by two‐dimensional polyacrylamide gel electrophoresis (2‐D PAGE) and mass spectrometry (MS). The
Proteomics to study genes and genomes
TLDR
Proteomics can be divided into three main areas: protein micro-characterization for large-scale identification of proteins and their post-translational modifications; ‘differential display’ proteomics for comparison of protein levels with potential application in a wide range of diseases; and studies of protein–protein interactions using techniques such as mass spectrometry or the yeast two-hybrid system.
Current two‐dimensional electrophoresis technology for proteomics
TLDR
The current 2‐DE/MS workflow is described including the following topics: sample preparation, protein solubilization, and prefractionation; protein separation by 1‐DE with IPGs; protein detection and quantitation; computer assisted analysis of 2-DE patterns; protein identification and characterization by MS; two‐dimensional protein databases.
Plant proteome analysis
TLDR
An overview is given on proteome studies performed to analyze whole plants or specific tissues with particular emphasis on important physiological processes such as germination and the use of proteome approaches to investigate the interaction of plants with pathogens or with symbiotic organisms.
Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource
TLDR
The Gene Ontology (GO) project provides structured, controlled vocabularies and classifications that cover several domains of molecular and cellular biology and are freely available for community use in the annotation of genes, gene products and sequences.