The POU gene ceh-18 promotes gonadal sheath cell differentiation and function required for meiotic maturation and ovulation in Caenorhabditis elegans.

@article{Rose1997ThePG,
  title={The POU gene ceh-18 promotes gonadal sheath cell differentiation and function required for meiotic maturation and ovulation in Caenorhabditis elegans.},
  author={Kristie L. Rose and Virginia P. Winfrey and Loren H. Hoffman and David H. Hall and Toshiaki Furuta and David Greenstein},
  journal={Developmental biology},
  year={1997},
  volume={192 1},
  pages={59-77}
}
In Caenorhabditis elegans, specialized contractile myoepithelial cells of the somatic gonad, the gonadal sheath cells, are closely apposed to oocytes and are required for normal meiotic maturation and ovulation. Previously we found that mutations in the ceh-18 gene, which encodes a POU-class homeoprotein expressed in sheath cells, result in oocyte defects. To determine the basis for these oocyte defects, we have used time-lapse video Nomarski microscopy to observe meiotic maturation, ovulation… CONTINUE READING
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