The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients

@inproceedings{NezTorres2016ThePG,
  title={The PNPLA3 Genetic Variant rs738409 Influences the Progression to Cirrhosis in HIV/Hepatitis C Virus Coinfected Patients},
  author={Roc{\'i}o N{\'u}{\~n}ez-Torres and Juan Mac{\'i}as and Maria A Mancebo and Mario Frias and Giovanni Dolci and Francisco T{\'e}llez and Dolores Merino and Nicol{\'a}s Merchante and Jes{\'u}s M G{\'o}mez-Mateos and Giovanni Guaraldi and Antonio Rivero-Juarez and Juan A Pineda and Luis M Real},
  booktitle={PloS one},
  year={2016}
}
Contradictory data about the impact of the rs738409 steatosis-related polymorphism within PNPLA3 gene on liver fibrosis progression in HIV/hepatitis C virus (HIV/HCV)-coinfected patients have been reported. Our objective was to test whether this, and other polymorphisms previously related to fatty liver disease in HIV infection linked to SAMM50 or LPPR4 genes, influence liver fibrosis progression in HIV/HCV-coinfected individuals. Three hundred and thirty two HIV/HCV-coinfected patients who… CONTINUE READING

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