The PH domain of the yeast GEF Rom2p serves an essential function in vivo

Abstract

In a screen designed to identify new upstream components of the Pkc1p-MAP kinase signal transduction pathway that responds to cell wall damage in yeast, we identified a new mutant allele of the ROM2 gene, which encodes a GDP/GTP exchange factor that acts on Rho1p. This allele, originally termed ubk1 (upstream of Bck1p) encodes a truncated protein that lacks… (More)
DOI: 10.1007/s004380100579

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@article{Lorberg2001ThePD, title={The PH domain of the yeast GEF Rom2p serves an essential function in vivo}, author={Anja Lorberg and Jeanne L. Jacoby and H. -J. Schmitz and J. Heinisch}, journal={Molecular Genetics and Genomics}, year={2001}, volume={266}, pages={505-513} }