The P2Y agonist UTP activates cutaneous afferent fibers.

@article{Stucky2004ThePA,
  title={The P2Y agonist UTP activates cutaneous afferent fibers.},
  author={Cheryl L Stucky and Karen A Medler and Derek C. Molliver},
  journal={Pain},
  year={2004},
  volume={109 1-2},
  pages={36-44}
}
The majority of adenosine triphosphate (ATP)-induced nociceptive transduction and pain has been attributed to ionotropic P2X3 receptors. Metabotropic P2Y receptors, some of which bind pyrimidines as well as purines, have received little attention. Here we have examined the ability of P2Y receptor signaling to evoke action potential firing in functionally… CONTINUE READING