The Overlap in the Genetic Pathogenesis of Ulcerative Colitis and Irritable Bowel Syndrome

@article{Kamiya2013TheOI,
  title={The Overlap in the Genetic Pathogenesis of Ulcerative Colitis and Irritable Bowel Syndrome},
  author={Takeshi Kamiya},
  journal={Digestive Diseases and Sciences},
  year={2013},
  volume={58},
  pages={3379-3381}
}
Ulcerative colitis (UC) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract. Although the etiology of UC remains unclear, genetic and environmental factors may contribute to its pathogenesis. Several genetic studies in Western and Eastern countries have reported associations between a number of polymorphisms and UC risk. Irritable bowel syndrome (IBS) is one of the most common chronic functional bowel disorders in which abnormal discomfort or pain is associated with… CONTINUE READING