The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium

@inproceedings{Baudequin2017TheOA,
  title={The Osteogenic and Tenogenic Differentiation Potential of C3H10T1/2 (Mesenchymal Stem Cell Model) Cultured on PCL/PLA Electrospun Scaffolds in the Absence of Specific Differentiation Medium},
  author={Timoth{\'e}e Baudequin and Ludovic Gaut and Marc Mueller and Angela Huepkes and Birgit Glasmacher and Delphine Duprez and Fahmi Bedoui and C{\'e}cile Legallais},
  booktitle={Materials},
  year={2017}
}
The differentiation potential of mesenchymal stem cells (MSC) has been extensively tested on electrospun scaffolds. However, this potential is often assessed with lineage-specific medium, making it difficult to interpret the real contribution of the properties of the scaffold in the cell response. In this study, we analyzed the ability of different polycaprolactone/polylactic acid PCL/PLA electrospun scaffolds (pure or blended compositions, random or aligned fibers, various fiber diameters) to… CONTINUE READING

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