The Orientation of Cell Divisions Determines the Shape of Drosophila Organs

  title={The Orientation of Cell Divisions Determines the Shape of Drosophila Organs},
  author={Luis Alberto Baena-Lopez and Antonio Baonza and Antonio Garc{\'i}a-Bellido},
  journal={Current Biology},
Organ shape depends on the coordination between cell proliferation and the spatial arrangement of cells during development. Much is known about the mechanisms that regulate cell proliferation, but the processes by which the cells are orderly distributed remain unknown. This can be accomplished either by random division of cells that later migrate locally to new positions (cell allocation) or through polarized cell division (oriented cell division; OCD). Recent data suggest that the OCD is… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 144 extracted citations

Organ Shape: Controlling Oriented Cell Division

Current Biology • 2005
View 4 Excerpts
Highly Influenced

Cell Division Orientation in Animals

Current Biology • 2011
View 5 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 32 references

Planar cell polarity Current Biology

Y. Gong, C. Mo, S. E. Fraser
Nature 430, • 2004
View 3 Excerpts

Planar polarity from flies to vertebrates.

Journal of cell science • 2004
View 2 Excerpts

Determining the role of patterned cell proliferation in the shape and size of the Drosophila wing.

Proceedings of the National Academy of Sciences of the United States of America • 2002
View 9 Excerpts

Similar Papers

Loading similar papers…