The Orientation of Cell Divisions Determines the Shape of Drosophila Organs

@article{BaenaLopez2005TheOO,
  title={The Orientation of Cell Divisions Determines the Shape of Drosophila Organs},
  author={Luis Alberto Baena-Lopez and Antonio Baonza and Antonio Garc{\'i}a-Bellido},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={1640-1644}
}
Organ shape depends on the coordination between cell proliferation and the spatial arrangement of cells during development. Much is known about the mechanisms that regulate cell proliferation, but the processes by which the cells are orderly distributed remain unknown. This can be accomplished either by random division of cells that later migrate locally to new positions (cell allocation) or through polarized cell division (oriented cell division; OCD). Recent data suggest that the OCD is… CONTINUE READING

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Organ Shape: Controlling Oriented Cell Division

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