The Onset of Lactase Persistence in Europe

  title={The Onset of Lactase Persistence in Europe},
  author={Pascale Gerbault},
  journal={Human Heredity},
  pages={154 - 161}
  • P. Gerbault
  • Published 1 May 2014
  • Biology, Medicine
  • Human Heredity
The genomic region containing the lactase (LCT) gene shows one of the strongest signals of positive selection in Europeans, detectable using a range of approaches including haplotype length, linked microsatellite variation and population-differentiation-based tests. Lactase is the enzyme that carries out the digestion of the milk sugar lactose. Its expression decreases at some point after the weaning period is over in most mammals and in around 68% of all living adult humans. However, in some… 

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