The Olive Oil-Based Lipid Clinoleic Blocks Leukocyte Recruitment and Improves Survival during Systemic Inflammation: A Comparative In Vivo Study of Different Parenteral Lipid Emulsions
@article{Buschmann2015TheOO, title={The Olive Oil-Based Lipid Clinoleic Blocks Leukocyte Recruitment and Improves Survival during Systemic Inflammation: A Comparative In Vivo Study of Different Parenteral Lipid Emulsions}, author={Kirsten Buschmann and Johannes Poeschl and Natascha Braach and Hannes Hudalla and Navina Kuss and David Frommhold}, journal={Mediators of Inflammation}, year={2015}, volume={2015} }
Although fish oil-based and olive oil-based lipid emulsions have been shown to exert anti-inflammatory functions, the immunomodulating properties of lipids are still controversial. Therefore, we investigated the anti-inflammatory effect of three different parenterally administered lipid emulsions in vivo: olive oil-based Clinoleic, fish oil-based Smoflipid, and soybean oil-based Lipofundin. We observed leukocyte recruitment in inflamed murine cremaster muscle using intravital microscopy andβ¦Β
9 Citations
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SMOFlipid and ClinOleic result in similar oxidative stress statuses after they were stopped, and the results were not statistically significant, but the TAC increased while the TOS and OSI decreased in SMOFlipper group.
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