The Nottingham Prognostic Index applied to 9,149 patients from the studies of the Danish Breast Cancer Cooperative Group (DBCG)

@article{Balslev1994TheNP,
  title={The Nottingham Prognostic Index applied to 9,149 patients from the studies of the Danish Breast Cancer Cooperative Group (DBCG)},
  author={Ingegerd Balslev and Christen Kirk Axelsson and Karin Zedeler and Birgitte Bruun Rasmussen and Bendix Carstensen and Henning T. Mouridsen},
  journal={Breast Cancer Research and Treatment},
  year={1994},
  volume={32},
  pages={281-290}
}
In primary, operable breast cancer, the Nottingham Prognostic Index (NPI) based on tumour size, lymphnode stage and histological grade can identify three prognostic groups (PGs) with 10-year survival rates of 83%, 52%, and 13%. With the aim of defining a subset of patients having so good prognosis that adjuvant therapy can be withhold, the NPI was applied to a Danish population-based study group comprising 9,149 patients. As opposed to the British study, we used conventional axillary lymph-node… CONTINUE READING

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